SynthArenav0.3.0
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  3. AiZynthFinder Retro* (High) on mkt-lin-500
AiZynthFinder Retro* (High)
Benchmark
mkt-lin-500
Total Routes
8257
Executed
December 3rd, 2025
Duration
859.1 min
Total Cost
$2.56
Acceptable Routes
Available
Target 1 of 500
Overall Metrics
Performance metrics across all targets in the benchmark. Hover over values to see 95% confidence intervals.
SolvabilityTop-1Top-2Top-3Top-4Top-5Top-10Top-20Top-50Top-100Top-500Top-1000Top-10000
99.0%9.2%13.2%17.2%19.2%20.6%25.4%28.8%30.2%30.2%30.2%30.2%30.2%

n = 500 targets

Metrics by Route Length
Performance breakdown by acceptable route length.
LengthSolvabilityTop-1Top-2Top-3Top-4Top-5Top-10Top-20Top-50Top-100Top-500Top-1000Top-10000n
2100.0%25.0%39.0%49.0%54.0%56.0%66.0%71.0%75.0%75.0%75.0%75.0%75.0%100
399.0%7.0%10.0%14.0%15.0%19.0%27.0%34.0%35.0%35.0%35.0%35.0%35.0%100
4100.0%5.0%6.0%10.0%13.0%14.0%15.0%16.0%16.0%16.0%16.0%16.0%16.0%100
599.0%5.0%6.0%7.0%8.0%8.0%13.0%17.0%17.0%17.0%17.0%17.0%17.0%100
697.0%4.0%5.0%6.0%6.0%6.0%6.0%6.0%8.0%8.0%8.0%8.0%8.0%100

Confidence intervals available on hover. Reliability indicators show LOW_N (insufficient samples) or EXTREME_P (value near boundary).

n5-00022

6 stepsLinearHas Acceptable Routes

SMILES

COc1c(N2CCN(C(=O)COC(C)=O)CC2)cc(Br)cc1C(C)(C)C

InChiKey

HMTKDIMDUAJTBJ-UHFFFAOYSA-N

Prediction Route
Rank 1 • Length: 0 steps • Linear
Unsolved
Solvability evaluated against: ASKCOS Buyables Stock
View:
Single route available
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Rank:
Rank 1 of 1
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Hash: 0435074fe4762b667e4fdb9d8f842e1291b7cb6379c6981b2732562fe588e1af