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  3. AiZynthFinder MCTS (High) on mkt-lin-500
AiZynthFinder MCTS (High)
Benchmark
mkt-lin-500
Total Routes
7843
Executed
December 4th, 2025
Duration
173.2 min
Total Cost
$0.52
Acceptable Routes
Available
Target 1 of 500
Overall Metrics
Performance metrics across all targets in the benchmark. Hover over values to see 95% confidence intervals.
SolvabilityTop-1Top-2Top-3Top-4Top-5Top-10Top-20Top-50Top-100Top-500Top-1000Top-10000
98.4%17.4%21.0%24.0%27.2%30.4%33.4%35.0%35.0%35.0%35.0%35.0%35.0%

n = 500 targets

Metrics by Route Length
Performance breakdown by acceptable route length.
LengthSolvabilityTop-1Top-2Top-3Top-4Top-5Top-10Top-20Top-50Top-100Top-500Top-1000Top-10000n
2100.0%50.0%61.0%64.0%69.0%72.0%78.0%82.0%82.0%82.0%82.0%82.0%82.0%100
399.0%13.0%17.0%22.0%27.0%36.0%41.0%43.0%43.0%43.0%43.0%43.0%43.0%100
499.0%11.0%12.0%17.0%22.0%22.0%23.0%23.0%23.0%23.0%23.0%23.0%23.0%100
598.0%9.0%10.0%11.0%11.0%14.0%16.0%17.0%17.0%17.0%17.0%17.0%17.0%100
696.0%4.0%5.0%6.0%7.0%8.0%9.0%10.0%10.0%10.0%10.0%10.0%10.0%100

Confidence intervals available on hover. Reliability indicators show LOW_N (insufficient samples) or EXTREME_P (value near boundary).

n5-00022

6 stepsLinearHas Acceptable Routes

SMILES

COc1c(N2CCN(C(=O)COC(C)=O)CC2)cc(Br)cc1C(C)(C)C

InChiKey

HMTKDIMDUAJTBJ-UHFFFAOYSA-N

Prediction Route
Rank 1 • Length: 0 steps • Linear
Unsolved
Solvability evaluated against: ASKCOS Buyables Stock
View:
Single route available
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Rank:
Rank 1 of 1
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Hash: 0435074fe4762b667e4fdb9d8f842e1291b7cb6379c6981b2732562fe588e1af