Syntheseus LocalRetro on ref-lin-600 | SynthArena by isChemist Group

Syntheseus LocalRetroonref-lin-600

Part of the Syntheseus algorithm family

Community

3,645

Routes Found

154.2 min

Total Duration

$0.46

Cost

Overall Metrics

Performance metrics across all targets in the benchmark. Hover over values to see 95% confidence intervals.

Tier-0 valid	Solv-0[n5-stock]	Top-1	Top-3	Top-5	Top-10	Top-20	Top-50	Top-100
67.2%	67.2%	5.0%	8.5%	10.8%	13.0%	13.0%	13.0%	13.0%

n = 600 targets

Metrics by Benchmark Stratum

Target-level performance using RetroCast's exact reported strata.

Stratum	Tier-0 valid	Solv-0[n5-stock]	Top-1	Top-3	Top-5	Top-10	Top-20	Top-50	Top-100	n
depth 2	79.0%	79.0%	17.0%	22.0%	25.0%	29.0%	29.0%	29.0%	29.0%	100
depth 3	69.0%	69.0%	8.0%	15.0%	18.0%	22.0%	22.0%	22.0%	22.0%	100
depth 4	73.0%	73.0%	3.0%	8.0%	12.0%	13.0%	13.0%	13.0%	13.0%	100
depth 5	72.0%	72.0%	2.0%	4.0%	5.0%	7.0%	7.0%	7.0%	7.0%	100
depth 6	62.0%	62.0%	0.0%	2.0%	4.0%	6.0%	6.0%	6.0%	6.0%	100
depth 7	48.0%	48.0%	0.0%	0.0%	1.0%	1.0%	1.0%	1.0%	1.0%	100

Confidence intervals available on hover. Reliability indicators show LOW_N (insufficient samples) or EXTREME_P (value near boundary).

Target 1 of 600

Only with predictions

n5-00015

7 stepsLinearHas Acceptable Routes

SMILES

c1ccc(-c2cc3cc(-c4ccncn4)c(-c4ccco4)nc3[nH]2)cc1

InChiKey

GMOSJDXQORTJOO-UHFFFAOYSA-N

No predictions found for this target. The model did not generate any routes.